Qualitative chemical analysis of juice carica papaya shown in table1, which indicated that juice contents were. The qualitative test was justified by their color changes with their various. Carica papaya extract engaged in supply and exports of carica papaya extract also called papaya extract or paw paw extract. Hiv1 effect of carica papaya aerial parts polar extracts and also the investigation of the chemical content from the polar extracts of the plant. Antimicrobial screening and phytochemical analysis of carica papaya leaf extracts 1ekaiko marshall u, 2chiwendu stephen.
In some parts of the world, specially australia and some islands of the west indies, it is known as papaw, or pawpaw, names which are better limited to the very different, mainly wild asimina triloba dunal, belonging to the annonaceae. Asclepiadaceae as a herbal remedy for the management of sickle cell anemia. The therapeutic effects of carica papaya leaves are presumed to be due to several active components such as papain, chymopapain, cystatin, ltocopherol, ascorbic acid, flavonoids, cyanogenic glucosides and glucosinolates. Introduction pawpaw carica papaya is a member of caricaceae family. The carica papaya extract cpe have hepatoprotective effect against carbon tetrachloride intoxicated rats and it may be mediating its protective effects either by decreasing the metabolic activation of carbon tetrachloride, or by acting as a chainbreaking antioxidant for scavenging free radicals or by a combination of these effects. The basic constituents of the leaves of carica papaya. Role of carica papaya leaf extract for dengue associated. Antimicrobial screening and phytochemical analysis of. Carica papaya used in treatments of jellyfish, insect stings, skin lesions and improve damaged skin conditions. Pdf on jan 10, 2017, okpe oche and others published chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts find, read and cite all the research. The leaves and fruits of five carica papaya morphotypes were harvested from trees in home gardens in umuahia, abia state, nigeria. This document provides an overview of baseline biological information relevant to risk assessment of genetically modified forms of the species that may be released into the australian environment. They are characterized by multilateral pharmacological activity and broad spectrum of therapeutic actions. The stem, leaf and fruit of papaya contain plenty of latex.
Chemical composition of various parts of carica papaya linn. Sarcotesta showed higher percentages of ash, crude protein, and crude fiber than did endosperm, but was lacking in fat. Investigation of bioactive compounds with anticancer. Jan 30, 2011 the antifungal compounds of the le of c.
Chemical composition of various part of carica papaya plant are described table 5. Chemical composition of leaves, fruit pulp and seeds in. Investigation of bioactive compounds with anticancer potential in carica papaya leaves. Biochemical constituents in leaf of carica papaya scipress ltd. Pusa dwarf linn jyotsna kiran peter, yashab kumar, priyanka pandey and harison masih department of microbiology and fermentation technology, jsbb, shiats deemed to be university, naini, up, india 211008. Antimicrobial screening and phytochemical analysis of carica. Evaluation of nutritional components of carica papaya at. The antibacterial activities and chemical composition of. Phytochemical screening of the polar extracts of carica. Phytochemical examination of the leaves of carica papaya l. Its origin is in the tropics of the americas, perhaps from central america and southern mexico. The fruits of papaya are much sought after by human as valuable foodstuff and have antihypertensive activity. Pdf chemical composition of leaves, fruit pulp and seeds in.
This document provides an overview of baseline biological information relevant to risk assessment. The medicinal properties of papaya fruit and other parts of the plant are also well known in traditional system of medicine. Chemical composition and antifungal activity of carica. The qualitative phytochemical analysis of carica papaya leaves showed the presence of alkaloid, flavonoid, saponin, tannin and glycosides. Proximate composition, minerals, carica papaya, seeds, skin. Phytochemical screening, chromatographic studies and antibacterial activity of carica papaya leaves extracts international journal of medicinal plants and natural products ijmpnp page plates were then allowed for the prediffusion time of 15 minutes after which they were incubated for. Phytochemicals are chemical compounds that occur naturally in plants. Antifungal activity in ethanolic extracts of carica papaya. Carica papaya, chemical constituents, gcms analysis, antimicrobial activity. Department of biochemistry and bioprocess technology, jacob school of biotechnology and bioengineering, sam higginbottom institute of agriculture, technology and sciences, allahabad u. Chemical composition of leaves, fruit pulp and seeds in some carica papaya l morphotypes article pdf available january 2012 with,854 reads how we measure reads. The chemical constituents were analysed using gas chromatography mass spectrometry gcms. The seed is a rich source of proteins 278% undefatted, 444% defatted, lipids 283% undefatted and crude fibre 226% undefatted, 318% defatted. Papaya seed oil utilized in high amounts could lead to reduced risk of coronary heart disease.
Does carica papaya leafextract increase the platelet. Amongst such medicinal plants is pawpaw carica papaya. Frontiers bioguided fractionation of papaya leaf juice. Copious amounts of latex are found in the leaves, stems and fruits 10. The min c, thiamin, riboflavin, niacin, vitamin b6 fresh green tea is an antiseptic whilst the brown, and vitamin k bari et al. Chemical properties of carica papaya several chemical materials are reported in different parts of carica papaya. Pdf chemical constituents and nutrient composition of. Chemical composition of papaya carica papaya seeds.
The morphotypes were based on fruit shape and pulp colour and are oblong red, oblong yellow, pear orange, round orange and round yellow. The hypoglycemic activities of carica papaya have been previously described for its fruit and leaves aruoma et al. It was found that the yield of this alkaloid from the nigerian plants is markedly lower than the values reported for american and asian varieties. Review on nutritional, medicinal and pharmacological. Seeds of papaya cultivated in somalia, which accounted for about 16% of the fresh fruit weight, were divided into sarcotesta and endosperm. The high level of natural self defence compounds in the tree makes it highly resistant to insect and disease infestation 9. Pdf the leaves and fruits of five carica papaya morphotypes were. The min c, thiamin, riboflavin, niacin, vitamin b6 fresh green tea is an. Papaya is a small, bushy tree with a hollow trunk, large palmate leaves, and oblong smoothskinned fruits melons. Pawpaw carica papaya belongs to the family caricaceae with over twenty species but only one member of the genus carica is cultivated as a fruit tree, while the other three genera cyclicomorpha, jarilla and jacaratia are grown primarily as ornamentals. Each tree hortus third asserts papaya is technically a giant herb because it never produces true woody tissue typically has a single, unbranched, nonwoody trunk bearing the scars of old leaf bases. The collected latex was spread on trays and left for dry. The melons are usually picked in a green state and allowed to ripen.
K l krishna 1, m paridhavi 2 and jagruti a patel 3 1jss college of pharmacy, ss nagara, mysore570 015, karnataka, india 2rajiv gandhi institute of pharmacy, trikarpur671 310, kasargod district, kerala, india. The standard method of analysis used was able to identify really that carica papaya. It has been documented in literature for its use by natives of various parts of world and also for its antiinflammatory, antitumour, antidiabetic effects and many others. Chemical profile of unripe pulp of carica papaya o. Other studies showed that carica papaya fruit is a source of good componentsmany like. Fresh papaya leaves of average maturity were collected from the tropical fruit world, duranbah, nsw, australia 2817. The methanol and aqueous extracts of carica papaya were tested for their antihiv1 activity using the syncytia formation assay. Main chemical components are papain, chymopapain, pectin. Defatted and undefatted seeds of papaya carica papaya were analyzed for proximate composition, some toxicants, sugar composition, mineral content, physicochemical properties of the seed oil and the fatty acid spectrum of the seed oil. Antioxidant analysis of different parts of carica papaya abstract this study was conducted to compare the total antioxidant activity taa, total phenolic content tpc and total flavonoid content tfc from the different parts of papaya tree including their ripe and unripe fruit, seeds and the young leaves. Bioguided fractionation of papaya leaf juice for delineating the components responsible for the selective antiproliferative effects on prostate cancer cells saurabh pandey 1,2,3, carina walpole 2,3, paul n. Carica papaya leaf decoction, an australian aboriginal remedy, has been used widely for its. Carica papaya leaves extracts for the treatment of dengue fever. Antioxidant analysis of different parts of carica papaya.
Phytochemical screening confirmed the presence of folic acid, vitamin b. Effect of carica papaya leaf extract capsule on platelet. In table 2, the result of the mineral composition clearly showed that carica papaya leaves contain rich source of mineral elements. Scientific evaluation of a common belief in some parts of asia using a rat model volume 88 issue 2 adebowale adebiyi, p. Chemical composition of various parts of papaya plant 4, 10, 11 part constituents. Reports have also shown that the active compounds present in. Oloyede department of biochemistry, university of adoekiti, ekiti state, nigeria abstract.
Phytochemical and antioxidant nutrient constituents of. The leaf tea or extract has a reputation as carica papaya is a source of carotenoids, vita a tumor destroying agent walter 2008. Some chemical compounds occurring in carica papaya. It is a soft wooded singlestemmed perennial tree, 210 m in height, with a crown of large palmate leaves emerging from the. Routine crude drug assays and tests tor stetoidal saponins, flavonols, tannins, phenols, organic acids, unsaturated sterols and alkaloids have been made on the leaves of carica papaya l. Pdf chemical composition of leaves, fruit pulp and seeds. Carica papaya cp otherwise known as the papaya pear is found in most tropical and subtropical countries of the world. Carica papaya extract papaya extract, paw paw extract. Effect of drying methods on the phytochemicals composition. Leaves contain large amounts of alkaloids, carpaine and pseudocarpine which creates. Pdf background carica papaya, treelike herb, is cultivated in more than 50 tropical and subtropical countries in the world.
Chemical composition of various parts of carica papaya linn fruit protein, fat, fibre, carbohydrates, minerals. The alkaloid, carpaine, was isolated and identified. When ripe, the flesh is sweet and juicy and similar in taste to other melons. Pdf biochemical constituents in leaf of carica papaya. The antibacterial activities and chemical composition of extracts from carica papaya cv. These active principles or ingredients occur naturally in such plants bamisaye, et al. The different parts of the carica papaya plant including leaves, seeds, latex and fruit exhibited to have medicinal value. Pdf chemical composition of leaves, fruit pulp and seeds in some. Maradol leaves are a potential source of secondary metabolites with antifungal properties. Unripe pulp ofcarica papaya was screened to test for the presence of certain phytochemicals. The potential of male papaya flower as a functional ingredient for herbal green tea production was reported by evaluating its phytochemical constituents, nutritive compositions, sensory attributes, and market potential. Review on nutritional, medicinal and pharmacological properties of papaya carica papaya linn. Ogant department of biochemistry, division of biological sciences, university of nigeria, nsukka, nigeria received 15 december 1970 abstractthe alkaloid caxpaine has been isolated from the leaves of the nigerian variety of carica papaya l and some new derivatives of the.
Consensus document compositional consideration for new varieties of. Pdf chemical composition of papaya philippa c ojimelukwe. Solvent extraction and chemical characterization of papaya. Drying methods had significant p of the seeds, with freezedrying. Phytochemical screening, antimicrobial and antioxidant. Bunchytop, cucumber mosaic, ringspot, waialua virus, yellow crinkle and leafcurl ag. There were animal studies suggest that papaya leaf extracts have potential therapeutic effect on disease.
Sekaki hong kong to evaluate antibacterial activities and determine chemical composition of carica papaya cv. This study was carried out to screen the leaf extracts of p. Antibacterial activity of seed and leaf extract of carica. Consequently, the resulting nonwatersoluble material is generally considered as waste, and in comparison to the water soluble fraction, little is known regarding its chemical composition 15. Antibacterial activity of seed and leaf extract of carica papaya var. This work describes biochemical constituents of leaves of carica papaya. Carica papaya contains an enzyme known as papain which is present in the bark, leaves and fruit. The latex from unripe papaya fruit contain enzymes papain and chymopapain. Papaya carica papaya consumption is unsafe in pregnancy. Three samples of carica papaya leaves green, yellow and brown were collected randomly from ogbomoso town, oyo state, nigeria and analyzed for the phytochemical composition, vitamins and mineral constituents. Although these effects are largely attributed to the active components of these plant materials okenwa et al.
The leaves also contain active components such as papin,chymopapin cystain, ascorbic acid, flavournoids, cynogenic glucosides that increases. Papaya leaves have been used in the treatment of various ailments 2. Nutritional value 4 constituents ripe papaya green papaya water 89. Effect of proteolytic enzyme and fiber of papaya fruit on human digestive health by monica moralma garces ortega thesis submitted in partial fulfillment of the requirements for the degree of master of science in food science and human nutrition in the graduate college of the university of illinois at urbanachampaign, 2011 urbana, illinois. The aim of this study was to analyse the chemical composition and examine the antifungal activity of the eo extracted from the seeds of carica papaya linn. The fruits, leaves, seeds and stem of carica papaya contain novel biological active compounds, which are potent as therapeutics or useful in industrial processes. This result becomes so important when the usefulness of such minerals like ca, mg, na, k, fe and mn in the carica papaya leaves indicates the usefulness of the leaves in the coagulation of blood, the proper. The leaves are large 3060 cm long, yellowgreen to darkgreen in colour, palmatelylobed, arranged spirally and clustered at the crown. Green synthesis of silver nanoparticles using carica. The major constituent is benzyl isothiocyanate 9936%. Oil extract showed very high levels of oleic and palmitic acids. The papaya seed eo was analysed by gas chromatography. Antifungal activity in ethanolic extracts of carica papaya l. Since, each part of papaya tree possesses economic value, it is grown on commercial scale.
Phytochemical screening, chromatographic studies and. Introduction nutritionally, the major components of carica papaya family. Traditional aboriginal preparation alters the chemical. Phytochemical screening and hypoglycemic activity of. Other key contributions of this study are the investigation of bioactive compounds in c. Carica papaya, commonly called papaya, is a small, frosttender, succulent, broadleaf evergreen tree that bears papaya fruits throughout the year. Medicinal uses of carica papaya j nat ayurvedic med medicinal uses of carica papaya anitha b2, raghu n1, gopenath ts3, karthikeyan m4, gnanasekaran a4. Carica papaya is a fast growing, softwooded, herbaceous plant reaching 310 m in height. Sd on the phytochemicals composition and antioxidant activities of carica papaya seeds, a medicinal plant, was investigated. Phytochemical analysis of pawpaw carica papaya leaves. Chemical constituents and nutrient composition of carica. Sekakihong kong seed abstract ten solvents were used to extract phytochemicals from the peel of carica papaya cv.
Chemical composition of leaves, fruit pulp and seeds in some carica papaya. Authentic standard comparison with available reference compounds. Phytochemical screening and hypoglycemic activity of carica. The alkaloid carpaine has been isolated from the leaves of the nigerian variety of carica papaya l and some new derivatives of the alkaloid have been prepared. The latex was chemically investigated and found that it was rich in chymopapain and papain and the later is also known as vegetable pepsin 2. Moreover, the levels of these enzymes vary in the fruit. Frontiers bioguided fractionation of papaya leaf juice for. N2 1dept of plant science and biotechnology, abia state university, uturunigeria. Evaluation of nutritional components of carica papaya l. The seed is a rich source of proteins 278% undefatted, 444% defatted, lipids 283% undefatted and. Caricaceae for possible antioxidant phytochemicals, proximate nutrient constituents, amino acid composition and mineral content present in the samples using standard chemical and chromatographic procedures. Phytomedicines are parts of a plant or the whole plant that possess healing properties.
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